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Protein on Ozempic: What to Eat to Keep Your Muscle

Why protein matters on GLP-1 medicines like Ozempic, Wegovy, Zepbound, and Mounjaro, how much to aim for, and easy protein-first meals and orders.

By ProteinPlates Editorial TeamUpdated September 24, 2026 3 min read

Grilled salmon with vegetables, potatoes, and a small bowl of sauce
Photo by Orkun Orcan on Unsplash

This guide is about food only

It does not cover medicine doses or side effects. Your doctor or care team is the right place for those questions.

Why protein matters on a GLP-1 medicine

GLP-1 medicines like Ozempic, Wegovy, Zepbound, and Mounjaro help many people eat less and lose weight. But when you lose weight, you don’t only lose fat. You can also lose muscle.

In one large study of a GLP-1 medicine, about 38% of the weight people lost was lean mass, which includes muscle. A 2025 advisory from four US nutrition and obesity groups lists keeping muscle and bone as a key goal during treatment.

Muscle helps you stay strong, move well, and keep your energy up. Two things help protect it: enough protein and strength exercise.

How much protein do you need?

The 2025 advisory lists 1.2 to 1.6 grams of protein per kilogram of body weight a day during active weight loss. That is higher than the basic adult minimum of 0.8 g/kg.

The advisory also says that for people with obesity, using your full body weight can overestimate how much protein you need. Our protein calculator handles this for you. Pick “On a GLP-1 medication” as your goal.

Eat protein first

When you feel full fast, the first few bites matter most. The advisory suggests eating protein-rich foods first in a meal, so you get them in before you feel full.

Try this at each meal:

  1. Start with the protein: the chicken, eggs, fish, tofu, or yogurt.
  2. Then eat the vegetables.
  3. Finish with rice, bread, or other starches if you still have room.

Protein-rich foods that don’t take much room

These foods give you a lot of protein in a small portion:

FoodPortionProtein
Chicken breast, roasted4 oz (113 g)35 g
Cottage cheese1 cup (226 g)24 g
Plain Greek yogurt, nonfat1 cup (226 g)23 g
Canned tuna in water, drained4 oz (113 g)22 g
Firm tofu4 oz (113 g)20 g
Eggs3 large19 g
Lentils, cooked1 cup (198 g)18 g

Values come from USDA FoodData Central.

The advisory encourages protein from beans, peas, lentils, whole grains, dairy, seafood, eggs, and lean poultry.

Smaller meals, more often

If big meals feel like too much, try four or five smaller ones. Give each one a protein food. A cup of Greek yogurt at 3 p.m. counts just as much as the protein at dinner.

Eating out on a GLP-1 medicine

Look for orders with lots of protein in a smaller portion. Some good picks from our restaurant guides:

  • Chipotle: the High Protein - Low Calorie Bowl (35 g protein, 460 calories) and the High Protein-High Fiber Bowl (46 g protein, 14 g fiber). Chipotle labels both “GLP-1 Friendly.”
  • Chick-fil-A: 8 ct Grilled Nuggets have 25 g of protein for 130 calories.
  • Starbucks: Egg White & Roasted Red Pepper Egg Bites have 12 g of protein for 170 calories. A Grande Iced Sugar-Free Vanilla Protein Latte adds 29 g.
  • Subway: the Baja Chicken Protein Pocket has 24 g of protein for 330 calories.

See our list of chains with GLP-1 and high-protein menus for more.

Add strength exercise

Protein works best with strength exercise, like lifting weights, resistance bands, or bodyweight moves. The advisory lists resistance training as a key way to keep muscle. Ask your care team what is safe for you before you start.

The bottom line

On a GLP-1 medicine, aim for enough protein, eat it first, and add strength exercise when you can. Small, protein-rich meals and snacks make it easier.

Find your own daily protein target in 30 seconds.

Protein calculator

Frequently asked questions

How much protein should I eat on Ozempic or Wegovy?

A 2025 joint advisory lists 1.2 to 1.6 grams of protein per kilogram of body weight a day during active weight loss. For people with obesity, it notes that using your full weight can overestimate needs. Our calculator gives you a range, and your care team can help you fine-tune it.

What are good high-protein foods when I’m not very hungry?

Try foods that pack a lot of protein into a small portion: Greek yogurt, cottage cheese, eggs, canned tuna or salmon, chicken, tofu, and lentils. Eat the protein part of the meal first.

Do I need to lift weights too?

Strength exercise, along with enough protein, is one of the main ways the 2025 advisory lists for keeping muscle during weight loss. Ask your care team what kind of exercise is safe for you.

More for: On a GLP-1 medication, Women

Not medical advice. If you have kidney disease, diabetes, or take prescription medication, talk to your doctor or a registered dietitian before changing your protein intake. Read our full disclaimer.